My youngsters are generally as wild as cottontails... but not so fragile. Once caught (if they need treatment for a bad eye, for instance) they calm down fairly quickly, but they really do not enjoy being handled. That's okay with me, since it means I don't get attached. Our adults are more friendly (some of them started life in cages) but they still don't appreciate being picked up. It's the down side of colony rabbits, but they do have a much enhanced social life and their daily care is so much easier that I have no plans to go back to cages.