I forget, anyone try vaccines for P?
6th from the bottom.
http://goatsupplies.netfirms.com/vaccines.html
6th from the bottom.
http://goatsupplies.netfirms.com/vaccines.html
Anyone tired the Pasteurella vaccine?
- Thread starter Secuono
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OneAcreFarm
Well-known member
I have never heard of this vaccine or of the company that makes it....I sure don't want my rabbits to be ANYONE'S guinea pig.
Also found a list of drugs that work on P, but not always safe on rabbits or not tested.
http://pets.dir.groups.yahoo.com/group/ ... sage/10126
__________ Sun Jan 20, 2013 10:10 pm __________
"Pasteurella multocida is a bacterial pathogen that can cause significant disease and subsequent effects on research activities involving rabbits. Although several vaccines have been tested under laboratory conditions, field trials of vaccines for the control of P. multocida in rabbits are few. We used a potassium thiocyanate extract (PTE) produced from P. multocida serotype D:3,12,15 to vaccinate Pasteurella-free rabbits at their introduction into a colony having endemic infection with P. multocida serotype A:3. Groups of 15 rabbits were vaccinated either SC or IN with 1.0 mg PTE once weekly for 3 wk. In addition a control group was sham-vaccinated IN with saline. After the last vaccine dose had been administered, rabbits were housed with the general colony of a facility with endemic pasteurellosis. Serum samples obtained before and 5 and 24 wk after the first dose of vaccine were evaluated by ELISA for anti-PTE IgG. Rabbits were euthanized if found in poor clinical condition, and all remaining rabbits were euthanized 24 wk after initial vaccination. Clinical disease typical of P. multocida infection was observed in 10 of 15 saline-vaccinated rabbits, 4 of 15 IN PTE-vaccinated rabbits, and 1 of 15 SC PTE-vaccinated rabbits. Bacterial culture of the nasopharynx at the time of necropsy was positive for P. multocida in 10 of 15 control rabbits, 5 of 15 IN PTE-vaccinated rabbits, and 1 of 15 SC PTE-vaccinated rabbits. Anti-PTE serum IgG activity had developed in both IN- and SC-vaccinated rabbits by 5 wk, with significantly lower activity by 24 wk after initial vaccination. IgG activity was significantly greater in rabbits vaccinated SC compared with controls or those vaccinated IN. In summary, PTE can be used to stimulate protective immunity to a heterologous strain of P. multocida, with stronger immunity generated by SC than IN vaccination."
http://www.ncbi.nlm.nih.gov/pubmed/18210993<br /><br />__________ Sun Jan 20, 2013 10:12 pm __________<br /><br />What is IN?
I know what SC and IM mean, but never heard of IN..
http://pets.dir.groups.yahoo.com/group/ ... sage/10126
__________ Sun Jan 20, 2013 10:10 pm __________
"Pasteurella multocida is a bacterial pathogen that can cause significant disease and subsequent effects on research activities involving rabbits. Although several vaccines have been tested under laboratory conditions, field trials of vaccines for the control of P. multocida in rabbits are few. We used a potassium thiocyanate extract (PTE) produced from P. multocida serotype D:3,12,15 to vaccinate Pasteurella-free rabbits at their introduction into a colony having endemic infection with P. multocida serotype A:3. Groups of 15 rabbits were vaccinated either SC or IN with 1.0 mg PTE once weekly for 3 wk. In addition a control group was sham-vaccinated IN with saline. After the last vaccine dose had been administered, rabbits were housed with the general colony of a facility with endemic pasteurellosis. Serum samples obtained before and 5 and 24 wk after the first dose of vaccine were evaluated by ELISA for anti-PTE IgG. Rabbits were euthanized if found in poor clinical condition, and all remaining rabbits were euthanized 24 wk after initial vaccination. Clinical disease typical of P. multocida infection was observed in 10 of 15 saline-vaccinated rabbits, 4 of 15 IN PTE-vaccinated rabbits, and 1 of 15 SC PTE-vaccinated rabbits. Bacterial culture of the nasopharynx at the time of necropsy was positive for P. multocida in 10 of 15 control rabbits, 5 of 15 IN PTE-vaccinated rabbits, and 1 of 15 SC PTE-vaccinated rabbits. Anti-PTE serum IgG activity had developed in both IN- and SC-vaccinated rabbits by 5 wk, with significantly lower activity by 24 wk after initial vaccination. IgG activity was significantly greater in rabbits vaccinated SC compared with controls or those vaccinated IN. In summary, PTE can be used to stimulate protective immunity to a heterologous strain of P. multocida, with stronger immunity generated by SC than IN vaccination."
http://www.ncbi.nlm.nih.gov/pubmed/18210993<br /><br />__________ Sun Jan 20, 2013 10:12 pm __________<br /><br />What is IN?
I know what SC and IM mean, but never heard of IN..
MamaSheepdog
Well-known member
ChickiesnBunnies":3v1g6c3a said:
I think it is a typo, and they mean IM.
MamaSheepdog
Well-known member
MamaSheepdog":13yoe2mo said:
Correction!
Actually, it could be Intra-Nasal, which would stimulate the mucous membranes in the nasal passages.
3mina
Well-known member
Intra-Nasal would make sense since pasteurella presents as snot in some cases.
