The kbtatts pen doesn't seem to bother the buns too much when I use it, so I haven't even tried numbing.
(I am very light handed.)
The kits usually look a little annoyed with me, and flick their ears a bit, but remain friendly and receptive to petting and such. I had one wiggle out of the towel she was wrapped in to nose-bump me while I was working on her. :lol:
They give me the impression that they might be equating the feeling of the tattoo pen with the feeling of being over-groomed by another rabbit. Not pleasant, but that my intent may actually be affectionate. I've yet to see one show signs of fear or resentment afterwards.