The vet gave them Revolution drops. Not sure how long I should wait for the drops to have effect. It's been two days and so far I don't see an improvement. I have desinfected their place, so that they don't get reinfected. How would I check for syphilis though?
Revolution is a medicine usually prescribed for dogs and cats for various parasitic infestations (fleas, ear mites, ticks, heartworms, roundworms, mange). It would make sense that it would kill the types of mites rabbits get, as well. It is an off-label med for rabbits, but most meds are off-label for rabbits!
If what your rabbits have is a mite infestation, the mites should be dead within a day or two of treatment, but scabs caused by scratching will take a while to heal. If the crusts continue to proliferate you can feel pretty sure it's not just mites (though a secondary infestation of mites could certainly occur on rabbits that are immunocompromised by a concurrent venereal disease).
If rabbits have a fur mite infestation (
Cheyletiella parasitivorax), you should be able to actually see the mites. It's often called "walking dandruff" since the mites are whitish and once there are a lot of them they look like moving flakes of skin. Generally they're easiest to see along the back, especially in the shorter hair at the base of the neck.
https://gojackrabbitgo.com/fur-mites-in-rabbits/
If the rabbits have ear mites (
Psoroptes cuniculiis) you can't see the mites themselves as they stay deep in the ears, but the rabbit will develop what looks like dirt inside the ear canal, which eventually grows into thick crusts that can fill the ear. I've found that rabbits that have one type of mite often have both (again, an immunocompromised animal is more likely to contract additional parasites/diseases).
Image from
How to Treat Ear Mites in Rabbits (Naturally)
Treponematosis (aka vent disease, aka rabbit syphilis) can be deduced by its clinical signs, or positively diagnosed by dark-field microscopy, silver staining or serologic assays.
Here is some information from
Diseases of Research Animals - DORA University of Missouri - Comparative Medicine Program
Clinical Signs: Subclinical infections are common. Cutaneous lesions may be present on external genitalia, anus, muzzle, and eyelids. Erythema, edema, and papules at mucocutaneous junctions are early lesions followed by ulcers with epidermal proliferation and crust formation. Lesions can persist for extended periods (>5 mo). Reluctance to breed and decreased reproductive efficiency may occur.
Diagnosis: Diagnosis can be confirmed by scraping the skin lesion and examining a wet-mount with dark-field microscopy for characteristic morphology (spirochetes measure 6-15 µm by 0.1-0.2 µm) and motility (longitudinal rotation and flexion). Lesions can be biopsied and the organism can be identified on silver-stained sections. Serologic assays using
Treponema pallidum as the antigen may be used for diagnosis, PCR may also be used.