I dont remember how, but yes-- you can enter "known" genotypes-There is a little checkbox in hte 'information' sheet for each rabbit- indicating genotype/phenotype- along with a manual way to enter the genotype.- Also, if you have the the phenotypes of related rabbits, (half siblings, grandparents, etc, you can get a more accurate prediction-- I asked for the colors/marking of some related rabbits-- entered them into the pedigree program with some fictitious names(to indicate genetics info only) and came up with an amazing difference in the 'predicted offspring coloring. What I really like, is the program pulls this information from archioved rabbits in the pedigrees-- so you are not cluttering up the page of available rabbits with non-existant or sold/replaced rabbits.