I have a 5 year old doe that is just getting ready to wean her litter of 6 in a couple more weeks. As far as I know this was her first litter. I only worried about her having a trouble with kits being a bit to large. I used my smallest buck on her, who happens to be smaller than her.
We had a six year old doe that had a litter of four in September and raised all of them well. She's a Netherland Dwarf but a false dwarf, four is our largest litter to date as most of our Dwarfs have two or three after the peanuts.
My 3 year old doe just kindled (first timer) a healthy litter and my almost 5 year old proven doe just kindled also after a 2 year break from breeding. The buck was 5 years old also.