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Degenerative mielopathy? GOLPP!

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Degenerative mielopathy? GOLPP!

Post Number:#1  Unread postby Nika » Fri Dec 02, 2016 12:43 am


Anybody has any experiences with this?

We are in an initial stages of "diagnosis" (officialy it can be diagnosed only with autopsy :( ), CT with myelogram is perfect for a 10 year old, so we send urine and blood samples to Laboklin to determined whether he has the gene or not. Wobbly back legs, dragging his toes, etc.. Russian terrier, not really an affected breed.
Last edited by Nika on Fri Jan 27, 2017 3:46 am, edited 1 time in total.

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Re: Degenerative mielopathy

Post Number:#2  Unread postby SixGun » Fri Dec 02, 2016 9:16 am


We went through this with our Boxer. We actually put her on a pretty rigorous exercise schedule and changed her diet a bit. She did pretty good for about 6 months with only moderate progression. Unfortunately a tumor then developed and we lost the fight. She was 10 and had a great life otherwise!

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Re: Degenerative mielopathy

Post Number:#3  Unread postby Dood » Fri Dec 02, 2016 11:07 am


Diet can cause this

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Re: Degenerative mielopathy

Post Number:#4  Unread postby SixGun » Fri Dec 02, 2016 1:13 pm


Dood wrote:Diet can cause this


I'm not familiar with there being a diet cause, but merely how a diet can keep the nerves coated a little bit longer. What would be a cause other than genetic predisposition?

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Re: Degenerative mielopathy

Post Number:#5  Unread postby Dood » Fri Dec 02, 2016 2:11 pm


It has been a noted condition in carnivores fed an unbalanced diet

Diffuse osteopenia and myelopathy in a puppy fed a diet composed of an organic premix and raw ground beef

http://avmajournals.avma.org/doi/abs/10 ... 234.8.1041

Structural and Biochemical Changes in a Spinal Myelinopathy in Twelve English Foxhounds and Two Harriers

http://m.vet.sagepub.com/content/28/2/117.short


Role of Copper and Vitamin A Deficiencies Leading to Neurological Signs in Captive Cheetahs (Acinonyx jubatus) and Lions (Panthera leo) in the United Arab Emirates

http://file.scirp.org/Html/4-2701326_50617.htm

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Re: Degenerative mielopathy

Post Number:#6  Unread postby SixGun » Fri Dec 02, 2016 8:42 pm


The only case that seems to be relevant to degenerative myelopathy in an elderly canine is the second one in reference to the Foxhounds and those diets were severely skewed.
Often what we see in many breeds in that some are more predisposed genetically. The Boxer, Rhodesian Ridgeback, Corgi, French Bulldog amongst others. AKC US Breed Clubs for the more heavily effected breeds have developed a DNA test.

http://www.caninegeneticdiseases.net/DM/basicDM.htm

http://www.caninegeneticdiseases.net/DM/ancmntDM.htm

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Re: Degenerative mielopathy

Post Number:#7  Unread postby Nika » Sat Dec 03, 2016 2:39 am


SixGun wrote:We actually put her on a pretty rigorous exercise schedule and changed her diet a bit.


Can you tell me more? I feed him kinda mixed diet, a week of kibbles, a week raw (whole pray) and a week of cooked (meat, veggies, carbs). He really likes ruminant stomachs, but I believe that in research with foxhounds the condition was caused from unbalanced diet and not just because they ate stomachs. Right?

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Re: Degenerative mielopathy

Post Number:#8  Unread postby SixGun » Sat Dec 03, 2016 8:37 am


In the Fox hound study it appears they were ONLY fed cow stomachs. I could see how that would create quite the imbalance.

For our girl we kept her on the modified raw diet, (whole pretty rabbit and chicken) with a fast day and then kibble on rotation. However we upped the organ meat and bone content. From the occasional marrow bone for a treat she was given marrow bones often.

But I believe the exercise was most helpful. She always loved to swim so we took her in the pool three times a week and slow walks twice a day. It wasn't to tire her out, but just try and keep the nerve relays working as well as possible. We also started massage, especially in her hind end.

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Re: Degenerative mielopathy? GOLLP!

Post Number:#9  Unread postby Nika » Fri Jan 27, 2017 3:45 am


Ok, we came to the diagnosis - GOLPP. Polyneuropathy, laryngeal paralysis, disfunctional ezofagus.

Any experiences with this, maybe?

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